Tyrosine is a nootropic supplement. Also called L-tyrosine, it is an amino acid. Tyrosine is considered to be an essential building block for proteins. It has some benefits for the brain, mood, stress, and more. It enhances working memory, executive functions and lessens symptoms of ADHD. The amino acid is commonly found in food. But to get the nootropic benefits, you need purified tyrosine in a supplemental form.

Tyrosine supplies the body with what it needs to create three essential neurotransmitters. They include dopamine, norepinephrine, and adrenaline. Hence, getting enough tyrosine makes a significant difference in brain function.

Read on to learn more about Tyrosine as a supplement.

History of Tyrosine

The word “tyrosine” has a Greek origin. “Tryos” means cheese. Tyrosine was discovered in 1846 by German chemist Justus von Liebig. It was obtained as a product of degradation of cheese protein, casein. The non-essential amino acid with a polar side group was called Tyrosyl. Back then, it was referred to as a functional group or side chain. Later in 1883, nootropic tyrosine was synthesized in the laboratory. As a result, the structure of the synthetic supplement was determined.

It’s generally classified as a hydrophobic amino acid. Tyrosine is less of a phenylalanine and more hydrophilic. The compound is encoded by the codons UAU and UAC in messenger RNA.

How does it work?

It is a precursor to the essential neurotransmitters in the brain, without which the body can’t function properly. Tyrosine is vital when you are under stress and need to focus. With low levels, you might start to experience a mental wall.  

Production of dopamine

In the brain, Tyrosine is converted to L-DOPA to produce dopamine, a neurotransmitter. The hormone regulates reward and pleasure functions. It also enhances memory and motor skills, thus an important brain chemical. 

The unused dopamine is further converted into norepinephrine, another essential brain chemical. Dopamine also plays a role in the production of adrenaline.

Boost Adrenaline and noradrenaline

Together with dopamine, the three neurotransmitters make catecholamines. The hormones regulate several brain functions. The body uses tyrosine to make this chemical messenger useful for mental alertness. The hormones are responsible for the fight-or-flight response to stressful situations. Without them, the body won’t be prepared to fight or flee from a perceived threat, attack, or harm.

Precursor to hormones

Tyrosine is a precursor to thyroid hormones. The thyroid gland produces the hormone. Its primary role in the body is to regulate metabolism. Hormones triiodothyronine (T3) and thyroxine (T4) occur in the colloid of the thyroid. They are derived from Tyrosine.

Precursor to pigments

Melanin gives color to the skin, hair, and eyes. Tyrosine is a precursor to the pigment melanin. It gives dark-skinned people the characterized color.

Production of alkaloids

Through the latex of opium, poppy tyrosine is converted into alkaloid morphine. These have tons of functions in the body, such as :


Function of Tyrosine

Boost focus

Tyrosine is a nootropic that helps the brain deal with stress. The supplement keeps the brain performing at its best. More so, during stress and improves focus. As a result, the brain can tackle challenges without getting burned out.  

Cognitive performance

Acute stress caused by short-term stressors affects cognition. Tyrosine, however, prevents cognitive impairment during exercise. A dose of Tyrosine restores mental vigilance and reaction time when administered.

Improves mood

Tyrosine turns into dopamine, which controls stress and motivation. Dopamine also boosts the level of serotonin. The two play a critical role in regulating mood. Whenever you feel blue, you could increase your dopamine levels using tyrosine supplementation.

Treat depression

Tyrosine is used to treat depression. By improving your mood, the supplement can improve the symptoms of depression. Besides, it restores the body’s stress response-ability. This is done by maintaining normal levels of noradrenaline (norepinephrine) in the brain. As a result, it reduces the effect of stress-induced depression symptoms.

Improves mental performance

Everything you do generates some stressful experiences. The adverse effects of stress are manifested by decreasing neurotransmitters. This affects brain function, reasoning, memory, attention, and knowledge—the absence of a stressor due to tyrosine improved mental performance. As a result, the supplement increases brainpower.

Boost memory

Tyrosine supplements boost neurotransmitters production, which restores memory. It improves working memory during a mentally demanding task. Working memory is essential in concentration and following instructions.

How do you take Tyrosine?

The supplement can be taken by mouth or applied to the skin. You can buy the supplement on its own or in combination with another brain-boosting nootropic. 

Tyrosine can be taken thrice in a day, once in the morning and whenever you need a mental boost. The recommended dosage for cognitive benefit is 500 mg – 2000 grams each day. Take it an hour before exercise. A dose-ranging from 45-68 mg per pound of bodyweight works best for sleep deprivation.  

You can also take them in three daily doses. Taking it with vitamins B6, B9 (folate), and copper have shown high biodiversity. They boost the conversion of Tyrosine to brain chemicals.

However, higher doses result in gastrointestinal upset—thus the need to split the amount into 2 or 3, taken an hour before the stressful event.

Side effects

Tyrosine is safe when taken in doses up to 150 mg/kg each day. It should be taken for three months.

However, some people experience side effects, such as:


It is safe when applied to the skin.

6 Choline Bitartrate

Choline Bitartrate is a natural salt that the body produces in small amounts but could be ingested as a supplement. When choline combines with tartaric acid, it forms Choline Bitartrate. As a supplement, Choline Bitartrate falls under synthetic nootropic, a precursor to acetylcholine. Choline itself is an important essential nutrient. But, binding with tartaric acid increases bioavailability. More so, it is the most recognized form of choline. 

History of Choline bitartrate

Adolph Strecker discovered choline in 1862. Yet, the Food and Nutrition Board of the National Institute of Medicine declared it in 1998 in the US. 

Choline bitartrate acts as a source of choline. The supplement belongs to the class of nootropics known as intermediates. But it is the best source of choline and acetylcholine. They provide high levels of acetylcholine in the brain. This is used as a kicker to enhance the effect of racetams. 

How does it work?

Choline bitartrate supplement has several mechanisms of action. More precisely, choline participates in several critical biochemical pathways. Choline bitartrate has several ways it affects the brain positively. But three main effects as the main mechanisms of action are: 

Boosts acetylcholine production 

The supplements boost acetylcholine, a well-known neurotransmitter-tied brain function, and memory. , it is a precursor to acetylcholine. It improves the efficiency of communication between neurons in the brain. Thus, its importance in neural signaling boosts mental clarity, cognitive processing, and learning. 

Increase production of phospholipids

The body needs choline to synthesize Phosphatidylcholine and sphingomyelin. They are vital for cell membrane makeup. All plants and animal cells need choline to preserve their structural integrity. Besides, Phosphatidylcholine is a key component of conditional reservoirs of choline. This factors in acetylcholine production.  

Functions of Choline Bitartrate supplement

When you take this supplement, it acts as the main source of choline in the body. The primary function of choline in the body includes: 

Boost memory

Supplementing with choline bitartrate, as shown in several studies, improves memory. Besides, research shows poor memory in people with choline deficiency. Thus, Choline Bitartrate supplementation in such people boosts memory. 

Memory loss due to aging factors can be treated using a choline bitartrate. 

Mental Stimulation

Choline Bitartrate supplement improves mood and brain energy. Supplementing with choline bitartrate can make a huge difference when feeling down and less alert. Also, it increases the production of acetylcholine. 

Improves Sleep

The choline bitartrate supplement provides high levels of choline. It helps initiate rapid eye movements (REM). There are five stages of sleep. REM is considered to have the most impact when it comes to memory formation. It stores what was learned throughout the day. 

REM contributes to restful sleep through its impact on the stimulus barrier. Therefore, the brain ignores the noise and other input from the environment. It allows one to sleep without interruption. 

Help with Alzheimer’s-Type Dementia

Choline Bitartrate supplementation reduces the effect of Alzheimer-type dementia. It improves some cognitive performance functions such as:


Helpful with Bipolar Disorder

Choline bitartrate supplementation showed improvement in mood symptoms of Bipolar Disorder. This was evidenced in a small human study where patients were treated with choline bitartrate. The study also showed a rise in the concentration of choline-containing compounds in the basal ganglia region of the brain. 

How to take Choline bitartrate?

Choline is available in the body in small amounts. It is available for consumption in foods and dietary supplements. Choline bitartrate is one of the best choline sources. 

Choline food sources include: 

Breast milk also contains a high amount of choline. For supplementation, choline bitartrate is available in capsule, tablets, and powder form. The recommended daily dosage of choline bitartrate supplements differs in accordance to: 

The standard dose of Choline bitartrate supplement is 500 mg to 3,000 mg each day. You can also take the supplement twice a day with food. 

Higher doses can be taken as it is a water-soluble version of choline. Any excess amount of this choline source will cross the blood-brain barrier. 

Note many nootropic stacks on the market contain choline bitartrate formula. Even some brand name vitamins contain the Choline Bitartrate. 

Side Effects

The supplement is non-toxic, but high intake can result in toxicity with too much choline in the body. 

The most common side effect includes: 

If you experience trouble sleeping, stop using Choline Bitartrate supplementations. 


The choline bitartrate supplement is suitable for anyone looking for a high-quality source of choline. The supplement improves body composition and reduces body fat levels. 

As a Nootropic, choline bitartrate provides cognitive-enhancing benefits. The ingredient boosts brain function. You can buy high-quality choline bitartrate “stacks” in the US market.

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