Nootropics for Mood


We all have been there.When you’re in a bad mood, your whole day feels like it’s been ruined. On the flip side, when we’re in a good mood, we are more productive at work, have better relationships and are more healthy in general. What if, say, our mood could be improved through supplements or compounds? That is exactly what Nootropics claim to be capable of. If used safely, Nootropics enhances one’s mood. 

Nootropics can boost neurotransmitter levels(imbalance of neurotransmitters can cause anxiety, depression) and also brain activity to improve the state of mind. With its ability to regulate the production and release of important brain chemicals like neurotransmitters can help clear brain fog, reduce anxiety, increase mental clarity, and provide an overall mood boost. Nootropics guarantee healthy mood levels, enhance mental speed, and keep you alert. 


Top Mood Stacks for 2021


Here’s what our review team has deemed as some of the best nootropic stacks for mood. All products are thoroughly tested and rated based on various factors such as quality, transparency, ease of buying, pricing, etc. They are then recommended not only for their superior product quality, but also on the likelihood of us recommending them to our family and friends. 




Best Nootropics for Mood


1. 5-HTP

5-Hydroxytryptophan, also called 5-HTP, is a chemical by-product of L-tryptophan in our body. 5-HTP acts mainly by boosting levels of serotonin (a neurotransmitter)within the central nervous system. Neurotransmitters are responsible for boosting social behavior and mood.

Key Benefits

  • Reduces anxiety.
  • Improves the symptoms of a CNS disorder called Cerebellar Ataxia.
  • Alleviates pain, fatigue, morning stiffness.
  • Reduces stress and helps you relax.


According to a study called, Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode, 5-HTP has got antidepressant effects on patients with depression. 5-HTP treats depression by increasing serotonin levels, thus enhancing mood.



Biotin (or vitamin B7) is a water-soluble vitamin of the vitamin B-complex popular for its ability to process food into energy. Biotin as a nootropic substance improves the cognitive ability of an individual. It is often taken as a supplement by individuals to give their brain all the fuel it needs to function maximally.

Key Benefits

  • Provides the brain with energy.
  • Synthesizes Neurotransmitters.
  • Myelin production (important for the transfer of nerves signals)


Biotin deficiency can lead to several neurological symptoms learning disabilities, lethargy, depression. A study called, The neurology of biotinidase deficiency showed that biotin supplementation can resolve a lot of these problems.



Aniracetam is a synthetic nootropic compound which means it does not occur naturally in the body. Hence it has to be taken as a supplement. Aniracetam affects the brain positively in several ways. Aniracetam helps increase sociability and improved mood.

Key Benefits

  • Cognitive enhancer.
  • Neurotransmitter booster
  • Memory optimization
  • Anxiolytic and antidepressant properties


A study published in CNS Neuroscience & Therapeutics showed that when patients were treated with aniracetam, their emotional state was significantly improved at 3 months. The study also revealed a significantly better cognitive performance with aniracetam.



Sulbutiamine is a nootropic supplement that is synthetically produced by binding two thiamine molecules, also known as vitamin b1. It is responsible for converting carbohydrates into energy, which helps develop body cells’ growth and development. Sulbutiamine supplies the brain with vitamin B1, which in turn increases brain activity.

Key Benefits

  • Reduce fatigue.
  • Increase attention span.
  • Improve athletic performance.
  • Nerve Coordination


A study called, Role of the Synthetic B1 Vitamin Sulbutiamine on Health showed that sulbutiamine can have anti-fatigue, nootropic, and antioxidant effects. The study further says that there is a great potential for sulbutiamine use, well beyond its first described function (to increase thiamine tissue concentration).

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