Nootropics for Sleep


Sleep plays an important role in physical health. It is one of the main executive functions that is needed to maintain a healthy life. A good sleep cycle revitalizes your energy, helps maintain weight, lowers the risk of heart disease, and reduces stress.

Nootropics can help you get full deep sleep and wake up refreshed the next day. They help improve levels of Serotonin, known as a happy chemical that helps to generate drowsiness, and promotes regular sleeping. Nootropic supplements further affect the levels of melatonin, which is an important hormone that is responsible for a healthy sleeping cycle.


Top Sleep Stacks for 2021


We at Neurolifts tests nootropic products for 3-4 weeks before suggesting a nootropic supplement to our audience. Our reviewers thoroughly test the products and rate the brands based on various factors such as quality, transparency, ease of buying, pricing, etc. We choose top stacks based on our personal experience, how likely we recommend brands to our family and friends. 



Best Nootropics for Sleep


1. Melatonin

Melatonin (N-acetyl-5-methoxytryptamine) is often one of the “forgotten” hormones when it comes to health, easily overshadowed by more popular names like insulin, testosterone, and cortisol. It is produced by a small organ called the pineal gland nestled at the base of the brain. Melatonin regulates circadian rhythm, the body’s internal clock which controls everything from when you go to bed to your blood pressure and even digestion.

Key Benefits

  • Enhancing the quality of sleep
  • Alleviates anxiety and depression symptoms
  • Strengthens the Blood-Brain Barrier
  • Melatonin is Neuroprotective


A study called, The effectiveness of melatonin for promoting healthy sleep showed that the use of melatonin by healthy adults shows promise to prevent phase shifts from jet lag and improvements in insomnia.



Kratom comes from the leaves of an evergreen tree named Mitragyna speciose. Kratom acts as a brain stimulant when taken in small doses and makes the person feel more active mentally and physically. It works as a strong analgesic at a moderate dose and relieves pain, plus makes you feel relaxed.

Key Benefits

  • Anti-depressant and Anti-anxiolytic medicine.
  • Safe alternative to other drugs used for recreational purposes.
  • Can be used for treating withdrawal symptoms.


A study published in Phytomedicine journal clearly demonstrated that mitragynine exerts an antidepressant effect in the animal behavioral model of depression.



Phenibut is a nootropic and was discovered that at low levels of phenibut in the brain, it increases the level of dopamine. This increase in dopamine has been attributed to phenibut’s ability to boost memory and overall performance. It relieves symptoms of anxiety and insomnia. 

Key Benefits

  • Cognitive enhancer.
  • Anxiolytic and anti-depressant.
  • Treatment of Insomnia.
  • Helps with Alcohol withdrawal symptoms.


According to the study, Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug, Phenibut relieves tension, anxiety, and fear, to improve sleep in psychosomatic or neurotic patients; as well as a pre- or post-operative medication.


4. Magnesium

Magnesium helps in treating sleep disorders, improves sleep quality by helping to activate mechanisms that quiet and calm you. It plays an important role in muscle relaxation, thus helping you fall asleep.

Key Benefits

  • Keeps blood pressure normal.
  • Fights depression.
  • Has Anti-inflammatory benefits.
  • Can help prevent migraine.


 The study called, The effect of magnesium supplementation on primary insomnia in elderly stated that magnesium helps with insomnia, sleep efficiency, early morning awakening. 


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