December 7, 2020

Sulbutiamine is a nootropic supplement that is synthetically produced by binding two thiamine molecules, also known as vitamin b1. Thiamine is readily available in food like liver, dried milk, and eggs, amongst others. It is responsible for converting carbohydrates into energy, which helps develop body cells’ growth and development. 

Sulbutiamine is lipophilic, which means it dissolves in fats, unlike hydrophilic thiamine, i.e., it dissolves in water. Excess thiamine is not stored for long in the body, and therefore it needs to be consumed from time to time (which is one of the reasons for its deficiency), while excess Sulbutiamine can be stored in the body over a while. Sulbutiamine has been known to reduce fatigue, increase attention span, improve athletic performance, and brain activity. Sulbutiamine is a more productive form of thiamine, and research and experiment have shown that Sulbutiamine increases the thiamine levels in the brain.

Brief History

In the 1950s, after the second world war, Japan’s public health sector recorded widespread beriberi caused by thiamine deficiency. Beriberi was majorly caused by rice consumption, which was not a good source of thiamine. This problem became the bedrock of subsequent efforts to produce thiamine derivatives, which have a better bioavailability (the ability of a substance to be easily absorbed and used by the body) than thiamine. Although there are other thiamine derivatives that were synthetically produced, sulbutiamine was the best of them all. Thiamine deficiency was strategically treated by the administration of Sulbutiamine with foods that have low thiamine content. 

How Does It Work?

Sulbutiamine’s lipophilic property makes it easy for it to cross the blood-brain barrier (a barrier that prevents pathogens from causing infections to the brain) and increases the brain’s thiamine levels, i.e., it supplies the brain with more than enough vitamin B1, which in turn increases brain activity. Reviews from users of Sulbutiamine have shown that taking the prescribed Sulbutiamine dosages has enhanced the activity of the central nervous system. Sulbutiamine is available in capsule and tablet forms.

Sulbutiamine Usage

Usage of Sulbutiamine is dependent on many factors, like the age of the user, medical history, and other health conditions. On average, recommended Sulbutiamine dosages range between 200mg-400mg daily, spread out into two or three times. Depending on how good the effects are after 4-5 days, Sulbutiamine dosage can be increased from 400mg-600mg. If you are unsure about the right amount of Sulbutiamine dosage, visit your doctor or a certified medical practitioner for advice on how to use it.

Oral administration of sulbutiamine is the only known method of using the drug. Sulbutiamine’s solubility in fat is one reason why it is recommended that it be taken with food rich in fat, which includes coconut oil, peanut butter, and the likes.

Reports have also shown that Sulbutiamine’s high dosage resulted in side effects like headache, skin irritation, drowsiness, nausea, and insomnia. At most, the recommended dosage of Sulbutiamine is 600mg per day.

What are people saying about this drug?

Reports have shown that sulbutiamine has had a significant impact on its users’ overall well-being, from improving memory retention to reducing fatigue and improving performances. 

  • Memory

Choline is a substance found in foods like meat, fish, and dairy. It improves memory function and activity. Usage of sulbutiamine increases the level of choline in the brain and therefore aids better brain activity and retention of information in the memory.

  • Chronic Fatigue

Chronic fatigue affects an individual’s mental and physical activity over a long period of time, and getting enough rest has never been known to solve the problem. Sulbutiamine was initially created to treat this problem, so it comes as no surprise that at its best, sulbutiamine helps in reducing the adverse effects of chronic fatigue.

  • Depression

Sulbutiamine is a form of nootropic, i.e., a drug used to improve cognitive function, especially creativity and mental alertness. Sulbutiamine users have reported an improvement in their overall mood and mental health after using the right dosage of sulbutiamine over time.  

  • Nerve Coordination

Research by experts has suggested that usage of sulbutiamine daily for up to 7 weeks for the nerves and muscles’ activity in people who suffer from one form of nerve pain or another. Athletes use Sulbutiamine as a supplement to improve their performances.

  • Anxiety

Sulbutiamine is a derivative of vitamin b1, making sulbutiamine one of the best remedies for anxiety. The ease with which sulbutiamine synthesizes on entry into the circulatory system is similar to that of vitamin b1, only that sulbutiamine is better and much more effective against anxiety.


Sulbutiamine is one of the most popular and effective forms of nootropics available, and it is sometimes sold under the brand name of Arcalion. Sulbutiamine can be bought over the counter and online alongside other supplements as Stacks. There is insufficient evidence to back up the effects of sulbutiamine over a long period of time, but there are no known effects from a controlled usage over a short period of time. The best results are obtained when sulbutiamine is administered orally with a diet that has a high-fat concentration.

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